Volume 77 Jul/Dez
Sex Steroid Hormone Estrogen and Cognition
- Categoria: Volume 74 - Janeiro/Março de 2011
- Autor: Benedetto Arnone, Alessandra Cavicchio, Mario D’Amico, Antonella Gasbari, Enrico Patrono, Assunta Pompili, Maria Clotilde Tavares, Carlos Tomaz
- Páginas: 18
- Preço: Faça o cadastro para download
- ISSN: 1807-9865
- Biblioteca: Neurobiologia
- Ano: 2011
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Sex Steroid Hormone Estrogen and Cognition
Antonella Gasbarri1*, Assunta Pompili1, Benedetto Arnone1, Alessandra Cavicchio1, Enrico Patrono1, Mario
D’Amico1, Maria Clotilde Tavares2 and Carlos Tomaz2
ABSTRACT
The role of estrogens on sexual behavior in mammals is very well known; moreover, its effects on other functions, including cognition, have only recently been recognized. The present review summarizes research conducted in our laboratory and others with the aim of identifying the role of estrogen on cognitive functions. In the first section, we briefly describe the neurobiology of estrogen; in the second, we discuss the effects of estrogens on cognitive behaviors in mammals, as well as the physiological relevance of these effects and their applicability to human health and disease. The third section details the role of estrogens on working memory in humans and non human primates, and in rodents, and the concluding section briefly describes the relations between estrogens and the aging brain.
Keywords: estrogen, estrogen receptors, cognition, learning and memory, working memory.